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Vioxx was released on the United States public in 1999 and has been marketed and distributed in more than 80 countries. (In some countries, the same drug is marketed under the trademark CEOXX). Worldwide sales of Vioxx in 2003 were $2.5 billion. Over Ninety One Million people in the United States have been exposed to Vioxx since it's release, and it is estimated that approximately 100,000 people have suffered a sever reaction to the drug, up to and including death.